Legally or technically?
I've been uninspected throughout my ownership and it's been a slight inconvenience. I have surrender my plates every 2 years as I can't keep registering car that never been inspected, so I just keep getting new plates.
At the minimal amount of miles I drive it each year, being uninspected is hardly a problem in my world.
I'm only a few more years away from being 25 years and it not being a problem anymore.